Protein is something that all of us are concerned about, especially among the health conscious public. A high protein diet, as well as a low protein diet can both result in significant health problems. Understanding what a protein S deficiency is and how we can deal with it is critical to our health.
What is a protein s deficiency
Protein S deficiency is a condition in which the protein S in the blood plasma is low. Protein S is part of a group of proteins called anticoagulants, which work to prevent blood clots from forming.
Protein S deficiency can be inherited from either parent, or it can be acquired later in life. About half of cases are inherited, while the other half are acquired.
Inherited protein S deficiency may affect both males and females, but it’s rarer in females because of X-linked inheritance (the gene responsible for producing protein S is on the X chromosome). Acquired protein S deficiency occurs more often in females than males.
What are the symptoms of protein S deficiency?
People with this condition may not have any symptoms at all. However, some people experience bleeding problems, including:
Bleeding after surgery or an injury (postoperative bleeding)
Heavy menstrual periods (menorrhagia) or abnormal vaginal bleeding
Bleeding into joints (hemarthrosis), such as knee joint bleeding after bumping into something hard
Causes of a protein S deficiency
Protein S is a protein in the body that helps the blood to clot. It is also known as antithrombin III, an anticoagulant protein. Protein S deficiency is rare, but it can cause problems if you have it.
Protein S deficiency is a genetic condition that affects your ability to produce the protein called protein C and protein S. These proteins help the blood to clot properly. They also help prevent blood clots from breaking loose and moving through your bloodstream. Without enough of these proteins, you may develop dangerous clots in your veins or arteries that could block blood flow to your heart or brain.
People with a protein S deficiency are at increased risk for serious blood clots such as deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, or heart attack. They also may bruise more easily than other people because their blood doesn’t clot as well after injury occurs.
Symptoms of Protein S Deficiency
Protein S deficiency is rare, with only 1 in 10,000 having the condition. Protein S is a blood clotting protein that helps prevent clots from forming. It functions by binding to the coagulation factor II (prothrombin), which triggers the formation of thrombin, which ultimately leads to clot formation.1 People who have protein S deficiency are at an increased risk of developing venous thrombosis (blood clots) or deep vein thrombosis (DVT).2 Protein S deficiency can also cause hemorrhagic stroke and recurrent miscarriage.3
If you are experiencing any of these symptoms, please contact your doctor immediately:
Dizziness or fainting spells
Shortness of breath
Chest pain and difficulty breathing
Risks and complications of Protein S Deficiency
Protein S deficiency is a form of hemophilia that causes blood clots to form in the veins. It is an inherited disorder in which a person has a defective protein called protein S, one of several factors needed for normal blood clotting. Protein S deficiency is not a bleeding disorder but can cause bleeding when there are injuries or surgery if treatment with anticoagulants (blood thinners) is not started early enough.
Protein S deficiency occurs in about 1 in 2,000 men and 1 in 5,000 women. It is most common among people of Scandinavian descent, affecting about one in every 300 people who have this ancestry. Women with the condition have a 50% chance of passing it on to their children.
Protein S deficiency can be mild or severe, depending on how much protein S you have and how much it’s working. If you have low levels of protein S, your body may not make enough to stop blood from clotting too quickly after an injury or surgery. This can lead to excessive bleeding that can be difficult to control using standard treatments like aspirin or warfarin (Coumadin).
A protein S deficiency is a blood-clotting disorder that can cause a person to form clots
A protein S deficiency is a blood-clotting disorder that can cause a person to form clots. Protein S is a protein that helps the blood to clot normally. Without enough protein S, the risk of forming a clot increases.
Protein S deficiency is inherited and can affect people of all ages. It’s more common in people with other conditions that affect the immune system, such as lupus or rheumatoid arthritis. It may not be noticeable until you have an injury or surgery and your blood doesn’t stop bleeding as quickly as it should.
A clot can break off from an injured blood vessel and travel through the bloodstream until it lodges in another part of the body. This can cause serious problems such as deep vein thrombosis (DVT), stroke or heart attack.
The only treatment for this condition is prevention through anticoagulant therapy (blood thinners).
The blood protein S is the most important of several substances that help control the body’s blood clotting process.
The blood protein S is the most important of several substances that help control the body’s blood clotting process. When blood vessels are injured, platelets collect to form a plug at the site of injury. This plugs the hole and prevents further bleeding. At the same time, chemicals called prothrombin activators convert prothrombin into thrombin, which acts as an enzyme to promote clot formation.
If you have too little protein S in your blood, you may develop a condition called Protein S Deficiency Bleeding (PSDB). This condition can be life-threatening if you have any type of serious injury or surgery.
Protein S deficiency bleeding usually occurs within two weeks after an operation or childbirth (but can occur years later). If you have this type of bleeding, it may seem like you’re having heavy periods but it’s more serious than that. Bleeding can occur internally or externally through cuts or wounds on your skin. Internal bleeding can cause abdominal pain and swelling, paleness, rapid heartbeat and shortness of breath — all signs of shock (septicemia).
Look out for the symptoms of protein s deficiency and learn about treatment options
A protein s deficiency is a rare blood disorder that affects how your blood clots. This condition can cause excessive bleeding or bruising and may be life-threatening if not treated.
Protein S is an important protein in the blood that helps regulate clotting. It’s made by the liver, but it can also be taken as a medicine called activated protein C (Xigris) to treat some types of cancer.
Protein S deficiency is a rare condition that occurs in about 1 out of every 50,000 people. It’s more common in people with certain genetic conditions, such as hemophilia A or B.
The symptoms of protein S deficiency include:
- Easy bruising
- Heavy menstrual bleeding
- Excessive bleeding after surgery or dental procedures
A protein s deficiency can cause blood clots
This kind of deficiency is most frequently heard in women over the age of fifty. Most often, sufferers are perfectly healthy and able to enjoy normal levels of activity, with no symptoms to speak of until they suffer a seemingly unrelated serious injury or illness. Blood clots caused by protein s deficiency are rare, but if caught ahead of time can be treated and prevented.
